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Reel Two's SureGene Research published in JBCB

Paper reviews Reel Two-AstraZeneca gene name disambiguation system

Jul 28, 2005

Reel Two's work on gene name disambiguation is featured in the June 2005 issue of the Journal of Bioinformatics and Computational Biology (Vol 3. No. 3). The paper examines the colloboration between Reel Two and AstraZeneca in developing a system that solves the problem of filtering out gene name synonyms while performing literature searches.

Powered by Reel Two's Classification System, SureGene automatically assigns gene names to their Entrez-Gene ID in PubMed abstracts. The system discussed in the paper includes coverage for 8,300 human genes. Users can search by gene name, Entrez-Gene ID or keyword, and are offered a range of synonyms to choose from when an ambiguous gene name is entered. Results include all Entrez-gene IDs associated with the article, as well as a score showing SureGene's confidence that the article is indeed about the query gene.

Automated and manual validations, detailed in the paper, show that it is possible to achieve high quality gene disambiguation using scaleable automated techniques.

To view the full paper, click here.